Publications
Mesenchymal stromal (stem) cell therapy modulates miR-193b-5p expression to attenuate sepsis-induced acute lung injury
Dos Santos CC, Amatullah H, Vaswani CM, Maron-Gutierrez T, Kim M, Mei SHJ, Szaszi K, Monteiro APT, Varkouhi AK, Herreroz R, Lorente JA, Tsoporis JN, Gupta S, Ektesabi A, Kavantzas N, Salpeas V, Marshall JC, Rocco PRM, Marsden PA, Weiss DJ, Stewart DJ, Hu P, Liles WC. Eur Respir J. 2022 Jan 6;59(1):2004216. doi: 10.1183/13993003.04216-2020. Erratum in: Eur Respir J. 2023 Nov 9;62(5):2054216. doi: 10.1183/13993003.54216-2020. PMID: 34112731.
One genome, many cell states: Epigenetic control of innate immunity
Fraschilla I, Amatullah H, Jeffrey KL. Curr Opin Immunol. 2022 Apr;75:102173. doi: 10.1016/j.coi.2022.102173. Epub 2022 Apr 8. PMID: 35405493; PMCID: PMC9081230.
Epigenetic reader SP140 loss of function drives Crohn's disease due to uncontrolled macrophage topoisomerases
Amatullah H, Fraschilla I, Digumarthi S, Huang J, Adiliaghdam F, Bonilla G, Wong LP, Rivard ME, Beauchamp C, Mercier V, Goyette P, Sadreyev RI, Anthony RM, Rioux JD, Jeffrey KL. Cell. 2022 Aug 18;185(17):3232-3247.e18. doi: 10.1016/j.cell.2022.06.048. Epub 2022 Aug 10. PMID: 35952671; PMCID: PMC9442451.
Immune chromatin reader SP140 regulates microbiota and risk for inflammatory bowel disease
Fraschilla I, Amatullah H, Rahman RU, Jeffrey KL. Cell Host Microbe. 2022 Oct 12;30(10):1370-1381.e5. doi: 10.1016/j.chom.2022.08.018. Epub 2022 Sep 20. PMID: 36130593; PMCID: PMC10266544.
Human enteric viruses autonomously shape inflammatory bowel disease phenotype through divergent innate immunomodulation
Adiliaghdam F, Amatullah H, Digumarthi S, Saunders TL, Rahman RU, Wong LP, Sadreyev R, Droit L, Paquette J, Goyette P, Rioux JD, Hodin R, Mihindukulasuriya KA, Handley SA, Jeffrey KL. Sci Immunol. 2022 Apr 8;7(70). doi: 10.1126/sciimmunol.abn6660. Epub 2022 Apr 8. PMID: 35394816; PMCID: PMC9416881.
Sleep exerts lasting effects on hematopoietic stem cell function and diversity.
McAlpine CS, Kiss MG, Zuraikat FM, Cheek D, Schiroli G, Amatullah H, Huynh P, Bhatti MZ, Wong LP, Yates AG, Poller WC, Mindur JE, Chan CT, Janssen H, Downey J, Singh S, Sadreyev RI, Nahrendorf M, Jeffrey KL, Scadden DT, Naxerova K, St-Onge MP, Swirski FK. J Exp Med. 2022 Nov 7;219(11). doi: 10.1084/jem.20220081. Epub 2022 Sep 21. PubMed PMID: 36129517; PubMed Central PMCID: PMC9499822.